.Pharmacolibrary.Drugs.ATC.A.A02BC07

Information

name: Dexrabeprazole
ATC code: A02BC07
route: oral
compartments: 1
dosage: 10 mg
volume of distribution: 0.15 L
clearance: 0.28 L/h/kg
other parameters in model implementation

Dexrabeprazole is the (S)-enantiomer of rabeprazole, a proton pump inhibitor (PPI) used to reduce gastric acid secretion. It is indicated for the treatment of gastric and duodenal ulcers, gastroesophageal reflux disease (GERD), and other conditions related to excessive stomach acid. Dexrabeprazole is not widely approved or marketed independently but is primarily investigated as a potentially more potent and safer PPI compared to racemic rabeprazole.

Pharmacokinetics

Estimated typical pharmacokinetic parameters for healthy adult subjects administered oral dexrabeprazole, derived by analogy to racemic rabeprazole due to lack of published clinical PK data specifically for dexrabeprazole.

References

Revisions


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