.Pharmacolibrary.Drugs.ATC.A.A03AE01 .Pharmacolibrary.Drugs.ATC.A.A03AE01| name: | Alosetron | |
| ATC code: | A03AE01 | |
| route: | oral | |
| compartments: | 1 | |
| dosage: | 1 | mg |
| volume of distribution: | 65 | L |
| clearance: | 22 | L/h |
| other parameters in model implementation | ||
Alosetron is a potent and selective 5-HT3 receptor antagonist indicated for the treatment of severe diarrhea-predominant irritable bowel syndrome (IBS-D) in women who have not responded to conventional therapy. It is approved for restricted use in some countries due to concerns about rare but serious gastrointestinal adverse effects.
Pharmacokinetic parameters reported in healthy adult volunteers, both male and female, after a single oral administration.