.Pharmacolibrary.Drugs.ATC.A.A06AC07 .Pharmacolibrary.Drugs.ATC.A.A06AC07| name: | TriticumWheatFibre | |
| ATC code: | A06AC07 | |
| route: | oral | |
| compartments: | 1 | |
| dosage: | 5000 | mg |
| volume of distribution: | 1 | L |
| clearance: | 0 | L/h |
| other parameters in model implementation | ||
Triticum (wheat fibre) is a dietary fibre derived from wheat, classified as a bulk-forming laxative. It is used to treat constipation and to promote bowel regularity by increasing stool bulk. It is available as an over-the-counter supplement and is considered safe for general use, though not indicated for acute or severe constipation or in patients with intestinal obstruction. It is approved for use as a dietary supplement rather than as a prescription medication.
No published pharmacokinetic studies reporting absorption, distribution, metabolism, or excretion of wheat fibre as an active pharmacologically absorbed substance in humans. Dietary fibre is generally considered non-absorbable; pharmacokinetic parameters such as volume of distribution, clearance, and bioavailability are not typically defined for this agent.
Marklund, M, et al., & Kamal-Eldin, A (2013). Chain length of dietary alkylresorcinols affects their in vivo elimination kinetics in rats. The Journal of nutrition 143(10) 1573–1578. DOI:10.3945/jn.113.178392 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23946349