.Pharmacolibrary.Drugs.ATC.A.A16AX06 .Pharmacolibrary.Drugs.ATC.A.A16AX06| name: | Miglustat | |
| ATC code: | A16AX06 | |
| route: | oral | |
| compartments: | 1 | |
| dosage: | 100 | mg |
| volume of distribution: | 83.8 | L |
| clearance: | 6.9 | L/h |
| other parameters in model implementation | ||
Miglustat is an oral iminosugar used as a substrate reduction therapy for the treatment of type 1 Gaucher disease in adults with mild to moderate disease for whom enzyme replacement therapy is not an option. It is also approved for Niemann-Pick disease type C. It inhibits glucosylceramide synthase and thereby reduces the accumulation of glycolipid substrates.
Pharmacokinetic parameters for healthy adult volunteers after a single oral dose.