.Pharmacolibrary.Drugs.ATC.C.C07CA03 .Pharmacolibrary.Drugs.ATC.C.C07CA03| name: | PindololAndOtherDiuretics | |
| ATC code: | C07CA03 | |
| route: | oral | |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 2.5 | L |
| clearance: | 300 | mL/min |
| other parameters in model implementation | ||
This fixed-dose combination drug contains pindolol, a non-selective beta blocker, and a diuretic agent. Pindolol is used primarily to treat hypertension and angina pectoris. The combination with a diuretic allows for enhanced antihypertensive efficacy. This combination (ATC: C07CA03) has been previously marketed, but fixed combinations of pindolol and diuretics are not commonly used or approved in most contemporary formularies.
No specific pharmacokinetic studies were identified for the combination of pindolol and diuretics (C07CA03). Parameter estimates are provided based on separate literature for pindolol and typical thiazide diuretics in healthy adults.