.Pharmacolibrary.Drugs.ATC.C.C07FB12

Information

name: NebivololAndAmlodipine
ATC code: C07FB12
route: oral
compartments: 2
dosage: 5 mg
volume of distribution: 10 L
clearance: 150 ml/min
other parameters in model implementation

Nebivolol and amlodipine is a fixed-dose combination antihypertensive medication that contains nebivolol, a selective beta-1 adrenergic blocker with vasodilatory properties, and amlodipine, a long-acting dihydropyridine calcium channel blocker. The combination is approved and widely used today for the treatment of essential hypertension in adult patients where monotherapy is insufficient.

Pharmacokinetics

Estimated typical pharmacokinetic parameters for fixed-dose combination in adults after oral administration, based on individual data for nebivolol and amlodipine due to lack of published parameters for the combination product itself.

References

Revisions


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