.Pharmacolibrary.Drugs.ATC.C.C09DX05 .Pharmacolibrary.Drugs.ATC.C.C09DX05| name: | ValsartanAndNebivolol | |
| ATC code: | C09DX05 | |
| route: | oral | |
| compartments: | 1 | |
| dosage: | 160 | mg |
| volume of distribution: | 17 | L |
| clearance: | 1.7 | L/h |
| other parameters in model implementation | ||
Valsartan and nebivolol is a fixed-dose antihypertensive combination containing an angiotensin II receptor blocker (valsartan) and a beta-1 selective adrenergic blocker (nebivolol). This combination is used for the treatment of essential hypertension in adults and may provide synergistic blood pressure-lowering effects. It is approved for use in several countries.
No published study reports pharmacokinetic model parameters specifically for the valsartan/nebivolol fixed combination. Estimates are provided below based on known PK data for monotherapy in healthy adults.