.Pharmacolibrary.Drugs.ATC.D.D07XB30 .Pharmacolibrary.Drugs.ATC.D.D07XB30| name: | CorticosteroidsCombinationsEGBetamethasoneAndGentamicinTopical | |
| ATC code: | D07XB30 | |
| route: | topical | |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 1 | L |
| clearance: | 100 | mL/min |
| other parameters in model implementation | ||
A topical preparation combining a potent corticosteroid (betamethasone) with an aminoglycoside antibiotic (gentamicin) for the treatment of inflammatory skin disorders with suspected or confirmed secondary bacterial infection; currently approved and available in several countries.
Estimated typical pharmacokinetic parameters for betamethasone and gentamicin in topical combination creams in healthy adult subjects, based on published single-compound dermal absorption data; no direct clinical PK model for combination product available.