.Pharmacolibrary.Drugs.ATC.G.G03AA09 .Pharmacolibrary.Drugs.ATC.G.G03AA09| name: | DesogestrelAndEthinylestradiol | |
| ATC code: | G03AA09 | |
| route: | oral | |
| compartments: | 2 | |
| dosage: | 0.15 | mg |
| volume of distribution: | 1.5 | L |
| clearance: | 10.0 | L/h |
| other parameters in model implementation | ||
Desogestrel and ethinylestradiol is a combined oral contraceptive containing a progestogen (desogestrel) and an estrogen (ethinylestradiol), used for the prevention of pregnancy. It is widely approved and utilized globally as a contraceptive option.
Pharmacokinetic parameters derived from studies in healthy adult women using combined desogestrel 150 μg and ethinylestradiol 30 μg oral contraceptives.
Bergink, W, et al., & Qvist, I (1990). Serum pharmacokinetics of orally administered desogestrel and binding of contraceptive progestogens to sex hormone-binding globulin. American journal of obstetrics and gynecology 163(6 Pt 2) 2132–2137. DOI:10.1016/0002-9378(90)90553-j PUBMED:https://pubmed.ncbi.nlm.nih.gov/2147817