.Pharmacolibrary.Drugs.ATC.G.G03AB06 .Pharmacolibrary.Drugs.ATC.G.G03AB06| name: | GestodeneAndEthinylestradiol | |
| ATC code: | G03AB06 | |
| route: | oral | |
| compartments: | 2 | |
| dosage: | 0.075 | mg |
| volume of distribution: | 6.5 | L |
| clearance: | 0.58 | L/h/kg |
| other parameters in model implementation | ||
Gestodene and ethinylestradiol are components of a combined oral contraceptive pill used for birth control in women. The combination is widely used and approved for the prevention of pregnancy.
Pharmacokinetic parameters for healthy adult women after a single oral administration of one tablet containing 0.075 mg gestodene and 0.03 mg ethinylestradiol.
Kuhnz, W (1990). Pharmacokinetics of the contraceptive steroids levonorgestrel and gestodene after single and multiple oral administration to women. American journal of obstetrics and gynecology 163(6 Pt 2) 2120–2127. DOI:10.1016/0002-9378(90)90551-h PUBMED:https://pubmed.ncbi.nlm.nih.gov/2124087
Bergink, W, et al., & Qvist, I (1990). Serum pharmacokinetics of orally administered desogestrel and binding of contraceptive progestogens to sex hormone-binding globulin. American journal of obstetrics and gynecology 163(6 Pt 2) 2132–2137. DOI:10.1016/0002-9378(90)90553-j PUBMED:https://pubmed.ncbi.nlm.nih.gov/2147817