.Pharmacolibrary.Drugs.ATC.G.G03DA04_1 .Pharmacolibrary.Drugs.ATC.G.G03DA04_1| name: | Progesterone_1 | |
| ATC code: | G03DA04_1 | |
| route: | intravenous | |
| compartments: | 2 | |
| dosage: | 10 | mg |
| volume of distribution: | 13.8 | L |
| clearance: | 71.4 | L/h |
| other parameters in model implementation | ||
Progesterone is a natural steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis. It is used as a medication primarily for hormone replacement therapy, treatment of menstrual disorders, and as a component of hormonal contraceptives. Progesterone is approved for use today in various oral, vaginal, and injectable forms.
Pharmacokinetic parameters reported for healthy adult women after a single intravenous bolus dose administration.
Kharasch, ED, et al., & Cox, K (1997). Assessment of cytochrome P450 3A4 activity during the menstrual cycle using alfentanil as a noninvasive probe. Anesthesiology 87(1) 26–35. DOI:10.1097/00000542-199707000-00005 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9232131