.Pharmacolibrary.Drugs.ATC.J.J05AX28 .Pharmacolibrary.Drugs.ATC.J.J05AX28| name: | Bulevirtide | |
| ATC code: | J05AX28 | |
| route: | subcutaneous | |
| compartments: | 1 | |
| dosage: | 2 | mg |
| volume of distribution: | 3.32 | L |
| clearance: | 0.243 | L/h |
| other parameters in model implementation | ||
Bulevirtide is an entry inhibitor used for the treatment of chronic hepatitis B and D virus infection. It acts by binding to and blocking the sodium taurocholate co-transporting polypeptide (NTCP) receptor on hepatocytes, thereby preventing viral entry. Bulevirtide is approved for medical use in the European Union for chronic hepatitis D infection in adults with compensated liver disease.
Pharmacokinetics in healthy adult subjects following subcutaneous administration; population pharmacokinetic modeling.