.Pharmacolibrary.Drugs.ATC.M.M01CC02 .Pharmacolibrary.Drugs.ATC.M.M01CC02| name: | Bucillamine | |
| ATC code: | M01CC02 | |
| route: | oral | |
| compartments: | 1 | |
| dosage: | 100 | mg |
| volume of distribution: | 0.4 | L |
| clearance: | 2.4 | L/h |
| other parameters in model implementation | ||
Bucillamine is a disease-modifying antirheumatic drug (DMARD) structurally related to D-penicillamine. It is primarily used in Japan and South Korea for the treatment of rheumatoid arthritis and is not approved in most other countries. Bucillamine exerts anti-inflammatory and immunomodulatory effects, serving as a thiol donor with antioxidant properties.
Pharmacokinetic parameters estimated for healthy adult population, oral administration, based on analogies with D-penicillamine and available clinical summaries in Japanese prescribing information sources. No direct publication of detailed PK parameter values was found in the literature.