.Pharmacolibrary.Drugs.ATC.N.N05CC04

Information

name: Dichloralphenazone
ATC code: N05CC04
route: oral
compartments: 1
dosage: 100 mg
volume of distribution: 0.6 L
clearance: 2 L/h
other parameters in model implementation

Dichloralphenazone is a sedative-hypnotic compound composed of a 1:2 molar mixture of chloral hydrate and phenazone (antipyrine). It has been used primarily as an ingredient in combination medications for the short-term treatment of tension and vascular headaches (e.g., migraine). It is not widely used as a monotherapy and is rarely used today due to the availability of safer alternatives; its clinical use has declined in many countries.

Pharmacokinetics

No pharmacokinetic studies found in the literature for dichloralphenazone as a single entity. Estimates below are based on assumptions from its known components, typical clinical dosage, and standard oral absorption parameters in adults.

References

Revisions


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