.Pharmacolibrary.Drugs.ATC.N.N05CD11

Information

name: Loprazolam
ATC code: N05CD11
route: oral
compartments: 2
dosage: 1 mg
volume of distribution: 70 L
clearance: 2.5 L/h
other parameters in model implementation

Loprazolam is a short-acting benzodiazepine hypnotic used for the short-term management of severe insomnia. It acts via enhancing GABAergic neurotransmission and has anxiolytic, sedative, and muscle relaxant properties. Though it was previously used in several countries for sleep disorders, its clinical use has diminished with the availability of safer alternatives, and it is not widely approved or marketed today.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers, single oral dose administration.

References

Revisions


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