.Pharmacolibrary.Drugs.ATC.N.N06AX13 .Pharmacolibrary.Drugs.ATC.N.N06AX13| name: | Medifoxamine | |
| ATC code: | N06AX13 | |
| route: | oral | |
| compartments: | 1 | |
| dosage: | 150 | mg |
| volume of distribution: | 4.0 | L |
| clearance: | 15 | L/h |
| other parameters in model implementation | ||
Medifoxamine is an atypical antidepressant that was previously used primarily in France and some other countries. It functions mainly as a serotonin-norepinephrine reuptake inhibitor (SNRI) as well as a 5-HT2 receptor antagonist. It is no longer marketed or approved for therapeutic use due to concerns about adverse effects, including hepatotoxicity.
Pharmacokinetic parameters estimated for a typical adult based on known properties of similar SNRIs; no original human PK studies publicly available.