.Pharmacolibrary.Drugs.ATC.R.R01AA04_1 .Pharmacolibrary.Drugs.ATC.R.R01AA04_1| name: | Phenylephrine_1 | |
| ATC code: | R01AA04_1 | |
| route: | intravenous | |
| compartments: | 1 | |
| dosage: | 5 | mg |
| volume of distribution: | 340 | L |
| clearance: | 215 | L/h |
| other parameters in model implementation | ||
Phenylephrine is a selective α1-adrenergic receptor agonist used primarily as a decongestant, to increase blood pressure in hypotensive states, and as a mydriatic agent. It is commonly used in over-the-counter cold and allergy medications, and as a vasopressor in clinical settings. It is still approved and widely used today.
Pharmacokinetic parameters in healthy adult volunteers following intravenous administration.
Vincent, J, et al., & Reid, JL (1986). Racial differences in drug responses--a comparative study of trimazosin and alpha 1-adrenoceptor responses in normotensive Caucasians and West Africans. British journal of clinical pharmacology 21(4) 401–408. DOI:10.1111/j.1365-2125.1986.tb05214.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/3011048