.Pharmacolibrary.Drugs.ATC.R.R01AD12 .Pharmacolibrary.Drugs.ATC.R.R01AD12| name: | FluticasoneFuroate | |
| ATC code: | R01AD12 | |
| route: | intranasal | |
| compartments: | 2 | |
| dosage: | 110 | mg |
| volume of distribution: | 608 | L |
| clearance: | 58.7 | L/h |
| other parameters in model implementation | ||
Fluticasone furoate is a synthetic corticosteroid with potent anti-inflammatory activity, primarily used for the treatment of allergic rhinitis and asthma. It is approved for nasal and inhaled use and is commonly available as a nasal spray for allergic rhinitis.
Pharmacokinetic parameters in healthy adult volunteers after a single intranasal dose.
Hosseini, S, et al., & Golshahi, L (2019). . Journal of aerosol medicine and pulmonary drug delivery 32(6) 374–385. DOI:10.1089/jamp.2019.1523 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31464547
Khadka, P, et al., & Golshahi, L (2024). Anatomically-detailed segmented representative adult and pediatric nasal models for assessing regional drug delivery and bioequivalence with suspension nasal sprays. International journal of pharmaceutics 666 124743–None. DOI:10.1016/j.ijpharm.2024.124743 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39343330