.Pharmacolibrary.Drugs.ATC.V.V09IX02

Information

name: Iobenguane131i
ATC code: V09IX02
route: intravenous
compartments: 2
dosage: 3700 mg
volume of distribution: 3.5 L
clearance: 0.18 L/h/kg
other parameters in model implementation

Iobenguane (131I), also known as 131I-metaiodobenzylguanidine (131I-MIBG), is a radiopharmaceutical agent used primarily for diagnostic imaging and treatment of certain types of neuroendocrine tumors, such as pheochromocytoma and neuroblastoma. It is labeled with radioactive iodine-131 and selectively taken up by adrenergic tissue. 131I-MIBG is currently approved for therapeutic use in metastatic or relapsed high-risk neuroblastoma.

Pharmacokinetics

Pharmacokinetic parameters as reported in adult patients undergoing therapy for neuroendocrine tumors; data from published clinical studies and product information.

References

Revisions


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