.Pharmacolibrary.Drugs.ATC.V.V09IX13 .Pharmacolibrary.Drugs.ATC.V.V09IX13| name: | Methionine11c | |
| ATC code: | V09IX13 | |
| route: | intravenous | |
| compartments: | 2 | |
| dosage: | 370 | mg |
| volume of distribution: | 0.2 | L |
| clearance: | 10 | L/h |
| other parameters in model implementation | ||
Methionine (11C) is a radiolabeled form of the essential amino acid methionine, used as a positron emission tomography (PET) tracer in oncology to image protein synthesis in tumors, particularly gliomas and other brain tumors. It is not a therapeutic drug, but a diagnostic radiopharmaceutical and is not approved for therapeutic use.
Pharmacokinetic estimates are based on published PET imaging literature and radiopharmaceutical handling in adult humans without significant comorbidities; direct compartmental PK values are generally not published, so values are estimated by analogy to similar tracers and compartmental modeling in PET research.