.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A07D_Antipropulsives.A07DA53_LoperamideCombinations.LoperamideCombinations .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A07D_Antipropulsives.A07DA53_LoperamideCombinations.LoperamideCombinations| name: | LoperamideCombinations | |
| ATC code: | A07DA53 | |
| route: | oral | |
| compartments: | 1 | |
| dosage: | 4 | mg |
| volume of distribution: | 60 | L |
| clearance: | 800 | mL/min |
| other parameters in model implementation | ||
Loperamide, in combination with other agents, is an antidiarrheal medication used to manage symptoms of acute or chronic diarrhea. It acts as a peripherally acting μ-opioid receptor agonist, reducing intestinal motility and prolonging transit time. Loperamide combinations are commonly used for symptomatic relief and are still approved and in use today globally.
No specific pharmacokinetic parameters for loperamide in combination products (ATC A07DA53) found in the literature for healthy adults or population subgroups.