.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A10A_InsulinsAndAnalogues.A10AE30_InsulinDegludecAndLiragl.InsulinDegludecAndLiragl

Information

name: InsulinDegludecAndLiraglutide
ATC code: A10AE30
route: subcutaneous
compartments: 2
dosage: 16 mg
volume of distribution: 10.0 L
clearance: 0.03 L/h
other parameters in model implementation

Combination of insulin degludec, an ultra-long-acting basal insulin analogue, and liraglutide, a GLP-1 receptor agonist. Used in the management of type 2 diabetes mellitus to improve glycemic control. Approved by regulatory agencies in many countries under the brand name Xultophy.

Pharmacokinetics

Pharmacokinetic parameters estimated for healthy adults based on published single-agent studies and product information. No single-population PK study directly available for the fixed combination product.

References

Revisions


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