.Pharmacolibrary.Drugs.C_CardiovascularSystem.C09A_AceInhibitorsPlain.C09AA15_Zofenopril.Zofenopril .Pharmacolibrary.Drugs.C_CardiovascularSystem.C09A_AceInhibitorsPlain.C09AA15_Zofenopril.Zofenopril| name: | Zofenopril | |
| ATC code: | C09AA15 | |
| route: | oral | |
| compartments: | 1 | |
| dosage: | 30 | mg |
| volume of distribution: | 96 | L |
| clearance: | 20 | L/h |
| other parameters in model implementation | ||
Zofenopril is an angiotensin-converting enzyme (ACE) inhibitor used for treatment of hypertension and heart failure. It is a prodrug hydrolyzed to its active form, zofenoprilat. Zofenopril has been approved for clinical use in several countries, primarily in Europe.
Pharmacokinetic parameters reported in healthy adult volunteers following a single oral dose.
Chen, BL, et al., & Zhang, W (2015). Clinical use of azelnidipine in the treatment of hypertension in Chinese patients. Therapeutics and clinical risk management 11 309–318. DOI:10.2147/TCRM.S64288 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25750535