.Pharmacolibrary.Drugs.D_Dermatologicals.D08A_AntisepticsAndDisinfectants.D08AC05_Polihexanide.Polihexanide .Pharmacolibrary.Drugs.D_Dermatologicals.D08A_AntisepticsAndDisinfectants.D08AC05_Polihexanide.Polihexanide| name: | Polihexanide | |
| ATC code: | D08AC05 | |
| route: | topical | |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 5 | L |
| clearance: | 0.1 | L/h |
| other parameters in model implementation | ||
Polihexanide (polyhexamethylene biguanide, PHMB) is a polymeric biguanide antiseptic and disinfectant used for wound care, contact lens disinfection, and as a preservative. It is primarily active against bacteria and some fungi and is valued for its good tissue tolerability. It is not systemically approved for internal administration and is mainly used topically.
No published pharmacokinetic studies in humans are available. Systemic absorption is considered negligible after topical application. Parameters below are estimates only.