.Pharmacolibrary.Drugs.D_Dermatologicals.D10A_AntiAcnePreparationsForTopicalUse.D10AX06_Clascoterone.Clascoterone .Pharmacolibrary.Drugs.D_Dermatologicals.D10A_AntiAcnePreparationsForTopicalUse.D10AX06_Clascoterone.Clascoterone| name: | Clascoterone | |
| ATC code: | D10AX06 | |
| route: | topical | |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 50 | L |
| clearance: | 18 | L/h |
| other parameters in model implementation | ||
Clascoterone is a topical androgen receptor antagonist used primarily in the treatment of acne vulgaris. It is approved for clinical use and is marketed as a 1% cream applied to the skin. Clascoterone acts locally to block androgen receptors, thereby reducing inflammatory and noninflammatory acne lesions.
Pharmacokinetic parameters were estimated for healthy adult subjects after topical application of clascoterone 1% cream. The data reflects systemic absorption from topical administration in humans.