.Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L01X_OtherAntineoplasticAgents.L01XX18_Tiazofurine.Tiazofurine .Pharmacolibrary.Drugs.L_AntineoplasticAndImmunomodulatingAgents.L01X_OtherAntineoplasticAgents.L01XX18_Tiazofurine.Tiazofurine| name: | Tiazofurine | |
| ATC code: | L01XX18 | |
| route: | intravenous | |
| compartments: | 1 | |
| dosage: | 1000 | mg |
| volume of distribution: | 20 | L |
| clearance: | 15 | L/h |
| other parameters in model implementation | ||
Tiazofurine is a synthetic antineoplastic agent structurally related to nicotinamide analogues. It was investigated as an anticancer agent, especially in the treatment of hematologic malignancies such as leukemia, but is not approved for therapeutic use today.
No published human pharmacokinetic models or parameters have been reported for tiazofurine in the literature as of the knowledge cutoff. The following values are estimated based on pharmacokinetics of structurally similar nucleoside analogs studied in oncology.