.Pharmacolibrary.Drugs.N_NervousSystem.N05A_Antipsychotics.N05AE03_Sertindole.Sertindole

Information

name: Sertindole
ATC code: N05AE03
route: oral
compartments: 2
dosage: 20 mg
volume of distribution: 20 L
clearance: 0.7 L/h/kg
other parameters in model implementation

Sertindole is an atypical antipsychotic drug, previously used in the treatment of schizophrenia. Due to concerns related to QT interval prolongation and risk of cardiac arrhythmias, its use is restricted or withdrawn in several countries. It is approved in some European countries but not in the United States.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers (male and female) after repeated oral administration.

References

Revisions


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