.Pharmacolibrary.Drugs.R_RespiratorySystem.R01A_DecongestantsAndOtherNasalPreparationsForTopical.R01AB03_Tetryzoline.Tetryzoline .Pharmacolibrary.Drugs.R_RespiratorySystem.R01A_DecongestantsAndOtherNasalPreparationsForTopical.R01AB03_Tetryzoline.Tetryzoline| name: | Tetryzoline | |
| ATC code: | R01AB03 | |
| route: | ocular | |
| compartments: | 1 | |
| dosage: | 0.5 | mg |
| volume of distribution: | 2.5 | L |
| clearance: | 1.2 | L/h/kg |
| other parameters in model implementation | ||
Tetryzoline (also known as tetrahydrozoline) is an imidazoline derivative acting as an alpha-adrenergic receptor agonist, primarily used as a topical decongestant in ophthalmic (eye drop) and nasal preparations for relief of redness or nasal congestion. It is still an approved medication in many countries.
No peer-reviewed human pharmacokinetic models or clinical PK parameter studies are published for tetryzoline. The following are rough estimates based on known drug class properties (topical ocular/nasal imidazoline alpha agonists) and limited animal/toxicological data.