 .Pharmacolibrary.Drugs.V_Various.V04C_OtherDiagnosticAgents.V04CK01_Secretin.Secretin .Pharmacolibrary.Drugs.V_Various.V04C_OtherDiagnosticAgents.V04CK01_Secretin.Secretin| name: | Secretin | |
| ATC code: | V04CK01 | |
| route: | intravenous | |
| compartments: | 1 | |
| dosage: | 0.2 | mg |
| volume of distribution: | 0.15 | L |
| clearance: | 28 | mL/min/kg |
| other parameters in model implementation | ||
Secretin is a peptide hormone produced in the duodenum that regulates water homeostasis and stimulates the pancreas to secrete bicarbonate-rich fluids. Clinically, synthetic or porcine secretin has been used as a diagnostic agent to stimulate pancreatic secretions in the evaluation of pancreatic exocrine function and in diagnostic tests for gastrinoma (Zollinger–Ellison syndrome). The use of secretin as a therapeutic agent is currently limited and it is not widely approved outside of diagnostic use.
Estimated pharmacokinetic parameters for intravenous administration in healthy adult individuals; no direct peer-reviewed publication of pharmacokinetics has been identified.