instant Sigmoid Emax effect
SigmoidEmaxEffect
instant Sigmoid Emax effect model. Effect E is calculated using an
equation
Emax * ch
E =
E0 + -----------
c50h +
ch
where c is the free concentration (either tissue or blood/plasma,
depending on the switch) at the BloodTissueConcentrationPort
connector.
Parameters
E0 -
baseline effect without drug influence
Emax
- maximal effect caused by drug
c50
- concentration producing half maximum effect
h -
hill coefficient
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