.Pharmacolibrary.Pharmacogenomics.PGx.phStatus

Information

Function phStatus(ph, a1, a2) maps a pair of star-alleles to a MetabolizerStatus according to the lists defined in the PhenotypeTemplate record.

Inputs

• ph – Phenotype: Must contain arrays poor, intermediate, rapid, and ultra.
• a1 – String: First allele identifier.
• a2 – String: Second allele identifier.

Output

• s – MetabolizerStatus: One of Poor, Intermediate, Normal, Rapid, or Ultra.

Algorithm

1. Initialize s = Normal.
2. If either allele is listed in ph.poor, set s = Poor.
3. Else if in ph.rapid, set s = Rapid.
4. Else if in ph.intermediate, set s = Intermediate.
5. Else if in ph.ultra, set s = Ultra.
6. Otherwise remain Normal.

Interface

function phStatus
  input Phenotype ph;
  input String a1;
  input String a2;
  output MetabolizerStatus s;
end phStatus;